Lipid Factor III transFatty Acids and Other Unidentified Factors in Oils

Nutritional values of vegetable oils have been evaluated primarily based on their FA composition. However, we began to realize that factors other than FAs (TG) influence animal physiology significantly at doses comparable to human intakes. Some kinds of vegetable oils and partially hydrogenated oils shortened the survival of stroke-prone SHR (SHRSP) rats unusually as compared with others. The free FA fractions derived from canola oil and hydrogenated-soybean oil exhibited no or significantly...

Hypertension Relationships to Coronary Heart Disease and Stroke

Hypertension is positively correlated with CHD and stroke mortality, and is generally accepted as one of the major risk factors for eventual CHD mortality. The term 'risk factor' generally indicates an associated occurrence, but it does not automatically mean that reducing a risk factor will be beneficial, as it would be for a causal risk factor. Although hypertension has a logical causal relationship to hemorrhagic stroke, its relationship to thrombotic or ischemic events remains to be...

From the Cholesterol Hypothesis to w6w3 Balance

Harumi Okuyama Yuko Ichikawa Yueji Sun Laboratory of Preventive Nutraceutical Sciences, Kinjo Gakuin University College of Pharmacy, Nagoya, Japan Department of Health Promotion and Preventive Medicine, Nagoya City University School of Medical Sciences, Nagoya, Japan Department of Psychiatry, Dalian Medical University, Dalian, China Institute of Natural Medicine, University of Toyama, Toyama, Japan 92 figures, 89 in color and 23 tables, 2007 Basel Freiburg Paris London New York Bangalore...

Effect of Dietary Cholesterol and PS Ratio of Fatty Acids on Total Cholesterol Short and Long Term Effects Differ

Increasing cholesterol intake elevates TC - A short-term effect Weggermans et al. 2001 , reproduced with kind permission from the American Journal of Clinical Nutrition . Copyright 2006. American Society for Nutrition. Increasing cholesterol intake elevates TC - A short-term effect Weggermans et al. 2001 , reproduced with kind permission from the American Journal of Clinical Nutrition . Copyright 2006. American Society for Nutrition. From 1974 to June 1999, 17 clinical studies (556 subjects)...

Three Different Types of Highly Unsaturated Fatty Acid

Saturated and monounsaturated FAs form the 9 type of HUFA Saturated FA (S) monounsaturated FA (M) ( Mead acid, 20 3 9) Animal fats animal fats Palm oil high-oleic vegetable oil (olive oil, canola) Linoleic acid forms the 6 type of HUFA Linoleic acid 7-linolenic acid dihomo-7-linolenic acid arachidonic acid (22 5w6) LA (18 2w6) GLA (18 3 w6) DGLA (20 3w6) AA (20 4w6) w6 eicosanoids (inflammatory mediators) a-Linolenic acid forms the type of HUFA a-Linolenic acid ALA (18 3w3) Leaves Seafood...

References

Adult Treatment Panel III of the National Cholesterol Education Program (NCEP) Bethes-da, National Heart, Lung, and Blood Institute, National Institute of Health, NIH Pub No 02-5215, 2002. AHA ACC Guidelines for Prevention of Heart Attack and Death in Patients with Atherosclerotic Cardiovascular Disease 2001 Update. Albert CM, Campos H, Stampfer MJ, Ridker PM, Manson JE, Willett WC, Ma J Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med 2002 346 1113-1118....

Anti Atherosclerotic Actions of w3 Fatty Acids

Comparison of plasma FAs and urinary eicosanoid metabolites - Inuit vs. Danes Data taken from Dyerberg et al. 1978 , and from Fischer et al. 1986 . Conclusions Unlike AA, EPA does not induce platelet aggregation in human platelet-rich plasma (PRP), probably because of the formation of thromboxane A 3 (TX A3) which does not have platelet aggregating properties. Moreover, EPA, like AA, can be utilized by the vessel wall to make an anti-aggregating substance, probably a delta-17-prostacyclin...

Clinical Evidence that w3 Fatty Acids Are Effective for the Primary and Secondary Prevention of Coronary Heart Disease

Morbidity of Inuit (Greenland Natives) and Danes Data taken from Kroman and Green 1980 and Lands 1986 . < is r & < is r & The study population (approximately 1,800 inhabitants) is one of the remaining whaling and sealing populations in Greenland. They were observed over the 25-year period 1950-1974 concerning the incidence of the diseases, which was based on all cases diagnosed in hospital during this period. The disease pattern of the Greenlanders differs from that of West-European...

Cholesterol Hypothesis Keys Equation and Key Concepts for New Interpretations

Cholesterol hypothesis, Keys' equation and key concepts Observations and questions on the relationship of dietary lipids, TC and CHD Cholesterol crystal deposits are found in atherosclerotic plaques Yes, but whether they are the cause or effect (consequence) of disease is not known. Positive correlations are noted between the TC and CHD events Yes, in some populations, but not all CHD events differ approx. 4- to 8-fold at the same TC value High LDL-C is often associated with more severe...

Reports on Japanese General Populations Showing Lower Mortalities from Cancer and All Causes in the Higher Total

Yao citizens (640 years old) with general medical examinations were followed for 8.5 years Baseline data were collected during 1975-1984 for citizens of Yao, Osaka (4069 years of age, n 12,187), and they were followed for 8.9 years on average up to 1988. Conclusion There was a significant inverse association of TC with total and cancer mortality for men, and no significant association for women. Our comments In a general population with a relatively small proportion of FH, no significant...

Two Dietary Imbalances Cause Diet Induced Dyslipidemias That Associate with Impaired Human Health

Many disorders in human health associate with diet-induced dyslipidemias that come from two readily prevented dietary imbalances imbalanced intake and expenditure of food energy and imbalanced intake of 6 and 3 fats. hypertriglyceridemia and NEFA as factors causing oxidative injury in vascular tissues Fat synthesis VLDL secretion High w6 in HUFA of tissue phospholipids , u6 reduc v,_ _> Eicosanoids Mevalonate Inflammatory cytokines proteins and proliferation Transient postprandial oxidant...

Data Rearranged to Convince Japanese People that High Total Cholesterol Is a Major Risk Factor for Coronary Heart

Apparent similarity in the TC and CHD relationship among MRFIT data (USA) and Japanese studies Adapted from the Japan Atherosclerosis Society Guidelines for Diagnosis and Treatment of Atherosclerotic Cardiovascular Diseases, 1997. Apparent similarity in the TC and CHD relationship among MRFIT data (USA) and Japanese studies Adapted from the Japan Atherosclerosis Society Guidelines for Diagnosis and Treatment of Atherosclerotic Cardiovascular Diseases, 1997. Conclusion These rearranged Japanese...