Future Directions

Despite several interventions designed to inhibit preterm labor and prolong pregnancy, the frequency of preterm birth continues to pose a major barrier to the health of newborns worldwide. Although current obstetric and neonatal strategies have resulted in improved rates of neonatal survival and an earlier threshold for viability, effective strategies for prevention of pre-term birth are urgently needed. As basic and translational research continues to reveal more of the complex endocrinological and immunological aspects of parturition, investigators must continue to search for biologically plausible new therapies to prevent preterm birth and develop markers or multiple markers to diagnose the syndrome accurately in its early stages.

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