Apoptosis is a highly orchestrated, genetically programmed process that allows cells to die in a controlled fashion (93,94). All cells have the intracellular machinery necessary for programmed cell death. Whether they use that machinery depends on the cell type, the tissue context, the presence or absence of physiological signals, and the extent to which a cell is damaged or dysfunctional. Like cellular senescence, apoptosis is a double-edged sword. Too little can cause damaged or dysfunctional cells to accumulate, whereas too much can cause tissue atrophy and degeneration.

How to Stay Young

How to Stay Young

For centuries, ever since the legendary Ponce de Leon went searching for the elusive Fountain of Youth, people have been looking for ways to slow down the aging process. Medical science has made great strides in keeping people alive longer by preventing and curing disease, and helping people to live healthier lives. Average life expectancy keeps increasing, and most of us can look forward to the chance to live much longer lives than our ancestors.

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