Clinical Comorbidity Underlined by Overlapping Biological Mechanisms

Sleep is altered in a variety of mental disorders, both as a consequence of the illness and secondary to pharmacological treatment. Mania and anxiety disorders can lead to sleep decrease, whereas anergic depression and negative-symptoms schizophrenia can lead to increases in the duration of sleep. As one of the few objective parameters to be investigated during a psychiatric interview, sleep may be viewed as the "temperature" of the psychiatric clinical exam. The extreme phenotype of narcolepsy has led to the identification of a family of brain peptides called hypocretins as involved in sleep regulation. Another promising line of research is represented by clock genes. Clock genes regulate circadian rhythms, are highly conserved from plants to man [82] and may be molecular substrates mediating the interface of sleep and psychiatric syndromes.

How To Win Your War Against Anxiety Disorders

How To Win Your War Against Anxiety Disorders

Tips And Tricks For Relieving Anxiety... Fast Everyone feels anxious sometimes. Whether work is getting to us or we're simply having hard time managing all that we have to do, we can feel overwhelmed and worried that we might not be able to manage it all. When these feelings hit, we don't have to suffer. By taking some simple steps, you can begin to create a calmer attitude, one that not only helps you feel better, but one that allows you the chance to make better decisions about what you need to do next.

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