• Lignocaine/lidocaine is indicated for refractory VF/VT when the first three defibrillator shocks have failed to produce a return of spontaneous circulation and when amiodarone is unavailable.

• It acts by suppressing the excitability of ventricular cells.

• The initial dose in VF is 100 mg and in haemodynamically stable VT, 50 mg should be administered intravenously.

• An infusion may be necessary according to local protocols.

• Side-effects are drowsiness, confusion and convulsions.

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