Diverticular Disease

dlverticulosis Definition and Pathology (Lancet 200*363:631)

• Acquired herniations of colonic mucosa and submucosa through the colonic wall

• More common on the left side (90%. mosdy sigmoid) than the right side of the colon

• May be a consequence of a low-fiber diet • colonic musculature contracting against small, hard stools — t intraluminal pressure — herniation of mucosa + submucosa

Epidemiology

• Affects 20-50% of persons over the age of 50; most prevalent in "Westernized" societies Clinical manifestations

• Usually asx. but can be complicated by diverticulitis or diverticular hemorrhage

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