• Infection with an obligate Gram-negative intracellular bacteria

• Human monocytic ehrlichiosis (Ehrlichiosis chaffeensis) (HME)

• Human granulocytic anaplasmosis (Anaplama phagocytophilum) (HGA)

• Transmission: HME by Amblyomma americanum, Dermacentor variabilis; HGA by Ixodes I Epidemiology

• Majority of HGA cases found in Rl. MN. CT. NY. MD

• Majority of cases of HME found in SE, southcentral, and mid-Atlantic regions of U.S. |

• Peak incidence spring and early summer

Clinical manifestations

• Fever, myalgia, malaise, headache, occasional cough, dyspnea, renal dysfunction

• Laboratory: leukopenia or neutropenia, thrombocytopenia, t aminotransferases. LDH. A^> Diagnosis

• Usually a clinical diagnosis

• Acute illness: intraleukocytic morulae on peripheral blood smear (rare); PCR; later: serology Treatment

• Doxycydine 100 mg PO bid

Was this article helpful?

0 0

Post a comment