Respiratory Acidosis

Etiologies

^p^ • CNS depression: sedatives. CNS trauma. Oj in chronic hypercapnia (4 hypoxemic drive)

• Neuromuscular disorders: myasthenia gravis. Guillain-Barre. poliomyelitis. ALS. muscular dystrophy, severe hypophosphatemia

• Upper airway abnormalities: acute airway obstruction, laryngospasm. obstructive sleep apnea, esophageal intubation

• Lower airway abnormalities: asthma. COPD

• Lung parenchyma abnormalities (often cause hypoxia t RR resp. alk., but eventual muscle fatigue — resp. acid.): pneumonia, pulmonary edema, restrictive lung disease

• Thoracic cage abnormalities: pneumothorax, flail chest, kyphoscoliosis

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