Rocky Mountain Spotted Fever RMSF

Microbiology

• Infection with Rickettsia rickcttsii (Gram © obligate intracellular bacterium)

• Transmitted by Dermacentor variabilis, Dermacentor andersoni

Epidemiology

• Coastal mid-Adantic, New England, midwest, northwest, southeast. Canada, Mexico.

Central America, and in parts of South America

• Peak incidence spring and early summer

Clinical manifestations

• Rash (2-3 d after onset): starts on ankles and wrists trunk, palms & soles

• Myalgias, N/V, occasionally abdominal pain

Diagnosis

• Usually a clinical diagnosis

• During acute illness can dx by examining skin bx for rickettsiae (Se 70%)

• 7-10 d after onset of sx. serology (indirect fluorescent antibody test) turns $ Treatment

• Doxycydine 100 mg PO bid

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