Factors Affecting Percutaneous Absorption Individual variation

Individual variation can be as severe a problem as for other drug delivery systems, for example the absorption of hydrocortisone can show nearly a ten-fold variation between individuals17. Thus dosage must be titrated to achieve a therapeutic benefit and the transdermal system does have the advantage in this respect that treatment can be stopped rapidly if too great a response is observed. It is straightforward to adjust the dose rate by varying the surface area of the device, although there are obviously practical limits to this.

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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