Parenteral Drug Delivery

INTRODUCTION INTRAVENOUS DELIVERY Physiology

Advantages and disadvantages of intravenous delivery Formulation considerations Devices and technologies Injected particulates Intravenous oxygen carriers INTRAMUSCULAR DELIVERY Physiology Pharmacokinetics Formulation considerations SUBCUTANEOUS DELIVERY Physiology

Subcutaneous colloidal delivery systems TISSUE DAMAGE AND BIOCOMPATABILITY

DRUG DISTRIBUTION FOLLOWING PARENTERAL ADMINISTRATION PROTEIN BINDING THE BLOOD-BRAIN BARRIER Physiology Uptake by diffusion Receptor-mediated transport Colloidal delivery REFERENCES

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