Physiological Pharmaceutics

Barriers to drug absorption Second Edition

Neena Washington, Clive Washington and Clive G.Wilson

First edition 1989

Second edition first published 2001 by Taylor and Francis 11 New Fetter Lane, London EC4P 4EE

Simultaneously published in the USA and Canada by Taylor and Francis Inc,

29 West 35th Street, New York, NY 10001

Taylor and Francis is an imprint of the Taylor & Francis Group This edition published in the Taylor & Francis e-Library, 2003. Publisher's Note

This book has been prepared from camera-ready copy provided by the authors.

© 2001 Neena Washington, Clive Washington and Clive G.Wilson

All rights reserved. No part of this book may be reprinted or reproduced or utilised in any form or by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying and recording, or in any information storage or retrieval system, without permission in writing from the publishers.

Every effort has been made to ensure that the advice and information in this book is true and accurate at the time of going to press. However, neither the publishers nor the authors can accept any legal responsibility or liability for any errors or omissions that may be made. In the case of drug administration, any medical procedure or the use of technical equipment mentioned within this book, you are strongly advised to consult the manufacturer's guidelines.

British Library Cataloguing in Publication Data

A catalogue record is available for this book from the British Library

Library of Congress Cataloguing in Publication Data Washington, Neena, 1961-

Physiological pharmaceutics: barriers to drug absorption/Neena Washington, Clive Washington, and Clive George Wilson.—2nd ed.

Previous ed. Physiological pharmaceutics: biological barriers to drug absorption/Clive George Wilson, Neena Washington. "Simultaneously published in the USA and Canada." Includes bibliographical references and index.

1. Drugs—Bioavailability. 2. Drugs—Dosage forms. 3. Drugs—Physiological transport.

4. Absorption (Physiology) I. Washington, Clive, 1957- II. Wilson, Clive George. III.

Wilson, Clive George. Physiological pharmaceutics: biological barriers to drug absorption. IV. Title.

RM301.6.W54 2000 615'.7-dc21

ISBN 0-203-48370-7 Master e-book ISBN

ISBN 0-203-79194-0 (Adobe eReader Format) ISBN 0-748-40610-7 (hbk) ISBN 0-748-40562-3 (pbk)

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