Vitamin effects

The consumption of large amounts of certain vitamins (doses of 1 g or more) has become popular with the general public. High doses of vitamin C do not materially affect the clearance of oral antipyrine which might suggest that vitamin C is without action on drug metabolism82; however, vitamin C is excreted by conjugation with sulphate. Drugs which are metabolised by sulphation such as ethinylestradiol would be likely to show competitive effects in their metabolism. Concomitant administration of ethinylestradiol with vitamin C resulted in a 50% increase in the steady state concentration of the drug, effectively converting a low dose oestrogen contraceptive pill to a high dose contraceptive pill83.

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Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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