Gallium-66 can be produced on a biomedical cyclotron via the 66Zn(p,n)66Ga nuclear reaction [13]. 66Ga is produced at Washington University using isotopically enriched 66Zn. The Zn can then be separated from the 66Ga either by cation exchange [14] or by solvent extraction techniques [15]. 66Ga is of interest because it is a medium half-life isotope (ti = 9.45 h) with potential for both imaging and therapy as a result of its high-energy positron (4.1 MeV) and other high-energy gamma rays [16].

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