Introduction

Copper has two natural occurring isotopes, 63Cu (69.2%) and 65Cu (30.8%). Several radionuclides can be produced for use in PET imaging, 60Cu, 61Cu, 62Cu and 64Cu, with 67Cu and 64Cu used for therapeutic purposes.

Ligand

H3[(5-MeOsal)3tame] H3 [(sal)3tame-O-n-Bu] H3 [(sal)3tame-O-iso-B H3 [5-MeO sal)3tame- O-sec- Bu] H3 [(5-MeOsal)3tame-O-n-Pr]

H OCH3

O(CH2)3CH3 H

OCH2CH(CH3)2 H OCH(CH3)CH2CH3 H O(CH2)2CH3 OCH3

Figure 11.3. Neutral salicyladimine ligands.

Et SH

HSX

Et

HS

Et4

f^Et

SH

HN HN

NH NH

SH

BAT-TECH

íns(2-mercatobenzyí)amme (S3N)

Figure 11.4. 68Ga-labelled myocardial and brain imaging agents.

Figure 11.4. 68Ga-labelled myocardial and brain imaging agents.

For a brief description of the radioactive properties and production see the section on copper radionuclides (above).

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