In 1997, the European Society of Human Reproduction (ESHRE) PGD Consortium decided to conduct a survey on the subject to determine the current status and future direction of governmental regulation of PGD. A questionnaire was sent to every centre practising PGD. The questionnaire sought information on the legal status of in vitro fertilization (IVF and PGD activities) throughout the world. This information was supplemented by a review of legal documents from the European Council and various state governments in the USA. Based on this review and the results of the questionnaire a summary was developed of the current status of PGD (Viville & Pergament, 1998).
Considerable differences in the regulatory oversight of PGD services exist among countries, ranging from total bans on any embryo manipulation to the almost complete absence of any regulations or authority. The survey of centres offering PGD services revealed common concerns about the creation of embryos for research, altering the pattern of normal embryo development, and the potential for misuse in the clinical application of PGD. These results indicated that PGD presents complex ethical challenges that will make developing a consensus and uniform regulations difficult even among European nations.
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