Hot Flash Remedy report

Hot Flash Remedy report

Heres what youll discover in The Hot Flash Remedy report: The herb from central Asia that can stop hot flashes in one week! (page 17) How your brain gets tricked into firing up the furnace and how to recalibrate it. (page 6) 7 lifestyle factors that increase your odds of suffering from hot flashes. (page 19) 9 food items that bring hot flashes on fast and furious! (page 10) The bean that actually makes hot flashes non-existent for women in other countries. (page 12) The secret ingredient in your fruit bowl that extinguishes the flame. (page 17) Why 6 meals a day are better than 3 and eating more often wont make you gain weight! (page 10) How common wildflowers hold the key to shutting down hot flashes. (page 16)

Hot Flash Remedy report Summary


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Gonadotropin Releasing Hormone Analogs

Gonadotropin releasing hormone analogs (GnRH) cause a temporaty medical menopause resulting in hypogonadism and hypoestrogenism by acting on the pituitary to reduce gonadotropin synthesis and secretion. Most of the side effects experienced occur because of the hypoestrogenic state including hot flashes, vaginal dryness, mood lability and decreased libido. The GnRH agonists have been shown to work well in reducing pain symptoms associated with endometriosis such as dys-menorrhea, dyspareunia, and noncyclic pelvic pain. GnRH agonists are often initiated with the onset of menses, but a more rapid response is observed with mid-luteal administration. A limit of 6 months per treatment course is required due to loss of bone mineral density during therapy, but this can be extended via the addition of 'add-back' therapy with estrogens. Retreatment with these drugs is supported by limited data. Several investigators have studied the use of GnRH agonists as surgical adjuncts. Their use...

Regimens for Hormone Replacement

Estrogen can be administered by oral, parenteral, topical or transdermal routes with similar effects and there are several different formulation choices available. Continuous estrogen therapy is recommended, though doses and route of administration can be changed relative to patient preference. Oral estrogen is the most popular in the United States. Transdermal estrogen patches avoid the first pass effect on the liver and offer the convenience of less frequent administration (usually weekly). Topical estradiol gel also avoids the first pass effect it is rubbed on the arm once daily. Finally, a slow release vaginal ring can provide sustained symptomatic relief for 3 months at a time. There are lower doses available for the patches and pills that prevent bone loss as well as hot flashes. It is important to remember that a woman Alternative Treatments for Hot Flashes There are a number of alternative therapies for women who are symptomatic from menopausal hot flashes but cannot take...

Differential Diagnosis

A comprehensive history and physical examination are indicated to rule out other possible causes of the emotional and physical symptoms of PMS. The differential diagnosis includes premenstrual molimina, hypothyroidism, perimenopause and major mood or anxiety disorders. Most ovulatory women experience some physical changes (e.g., breast tenderness, bloating, and food cravings) during the luteal phase. If these physical symptoms do not interfere with normal life functions, the term molimina can be applied. Hypothyroidism can share many of the same symptoms as PMS however there should be no cyclic variation. A thyroid stimulating hormone level is a sufficient screen, if warranted by clinical suspicion. There is also considerable overlap between the symptoms of perimenopause and those of PMS. Many women experience symptoms of emotional irritability, cyclic mastalgia, bloating and hot flashes as part of the perimenopause. It is likely that similar pathophysiologic factors mediate symptoms...

Hormonal Treatments

Progesterone has also been used for the treatment of premenstrual syndrome, but a recent meta-analysis found that progesterone and other progestogens were no more effective than placebo. In contrast, gonadotropin releasing hormone (GnRH) agonists, including leuprolide and buserelin, were superior to placebo in the reduction of premenstrual emotional (irritability, depression) and physical (bloating, breast tenderness) symptoms in four double-blind controlled studies. Although GnRH agonists may be effective for PMDD, the parenteral route of administration (for leuprolide), cost, and potential side effects, including hot flushes and vaginal dryness, make them a third line treatment strategy.

Metastatic disease

In a cross-sectional study of patients with metastatic disease using the SF-36, EORTC and a disease-specific module, patients in remission (hormone sensitive) showed similar scores to age-matched norms, whereas those with progressing disease showed lower scores for bodily pain, vitality, social function and mental health.73 However, no differences were seen in sexual function, sexual satisfaction, hot flashes or diarrhea.

The Transition

The early perimenopause is characterized by slowly declining ovarian function, increasing frequency of anovulatory cycles, irregular cycle lengths, fluctuating gonadotropin levels, and an overall increase in FSH and luteinizing hormone (LH) levels. FSH levels, in particular, may fluctuate widely, changing with each cycle, largely due to a decrease in the number of ovarian follicles. With loss of ovarian follicles as well as granulosa cells, inhibin levels, which normally provide negative feedback on the pituitary FSH secretion, decrease. This results in the loss of the negative feedback loop between inhibin and FSH, leading to an elevation of FSH levels. FSH levels trend upward starting in the late reproductive years, even before changes in the menstrual cycle, once inhibin levels fall low enough to allow a rise in FSH levels. Thus, the routine measurement of serum FSH to determine if a woman is perimenopausal can be misleading. Therefore, clinical evaluation becomes important in...

Vasomotor Symptoms

Vasomotor instability or the hot flash is a common complaint of the perimenopausal and menopausal woman, affecting 60 to 85 of all women. Hot flashes usually occur suddenly, though some women may experience an aura or premonition of the impending hot flash, and generally begin with an intense feeling of heat in the face and thorax. Visible flushing or reddening of the face and neck often follows, with a rise in heart rate and skin blood flow. Skin resistance drops rapidly, resulting in increased skin conductance of heat and a sensation of skin warmth. An increase in peripheral blood flow, heart rate, and finger temperature can result in palpitations and profuse sweating. Although hot flashes occur for 0.5 to 5.0 years on average after last menses, they may persist beyond five years, and up to 10 of women experience hot flashes for greater than 15 years. Their frequency ranges from 5 to 50 per day, with an average duration of 4 minutes. Women who have undergone surgical menopause are...

Ovulation Induction

Ovulation Stimulation

Complications of CC include OHSS and multiple pregnancies. Original reports demonstrated twin pregnancy rates of 10 and higher order multiple rate (triplets or greater) of 1 . Clinically significant OHSS is uncommon in CC stimulated cycles. Side effects of CC include breast tenderness, bloating, hot flashes, abdominal discomfort, and mood changes. A rare side effect is changes in vision or sensitivity to light, which requires immediate discontinuation of the medication, as continuation may cause permanent visual changes.

Black cohosh root

The alcoholic extract of black cohosh root is widely used by women in Europe and now the USA as a treatment for menopausal symptoms.54-56 Virtually all of the clinical studies have been done with one preparation, Remifemin, originally developed in Europe and now marketed in the USA. Many men with prostate cancer on hormonal therapy are using Remifemin or other black cohosh root preparations as treatment for their hot flashes and other symptoms of male menopause. Black cohosh was one of the medicinal plants widely used by various American Indian tribes and adapted by early European settlers as a treatment for rheumatism. The use of black cohosh for menopausal symptoms became widespread during the 1800s in both America and Europe. At present, virtually all significant clinical and laboratory investigation on black cohosh have been performed by European investigators. Numerous clinical trials, including randomized controlled trials, have compared Remifemin with placebo and a variety of...

Available Doses

Given neurontin have fewer hot flashes than those given placebo. Low dose progestins are effective in the treatment of menopausal symptoms to a moderate degree, but still a form of hormonal therapy and may be a source of concern in patients with a history of breast cancer. Two antihypertensives, clonidine and methyldopa, have been used to treat vasomotor symptoms, suggesting a role for adrenoreceptors in the physiology of these symptoms. Low dose clonidine, is partially effective in the relief of hot flashes, but for many women, adequate therapy requires substantial doses and severe side effects. Methyldopa, at doses of 500 to 1000 mg d, has been shown to be twice as effective as placebo for the treatment of hot flashes. Veralipride is a dopam-ine antagonist that has been shown to be active in the hypothalamus, effectively inhibiting flushing at a dose of 100 mg day. However, it is associated with major side effects such as galactorrhea and mastodynia. Bellergal is a combination of...

Combined Agents

Many women, resulting in night sweats, multiple episodes of awakening, and overall nonrestful sleep. The resulting decreased sleep efficiency caused by hot flashes may explain the associated chronic fatigue and irritability from which many menopausal women suffer. The most effective treatment for hot flushes is estrogen, which can be given through a variety of regimens, that are described below and listed in Tables