The management of Enterobius infection is more complex than the simple prescription of an effective anthelminthic agent. Benzimidazoles, such as mebendazole and albendazole, are active and piperazine and pyrantel can also be used (see below). It is usually necessary to treat the whole family to prevent re-infection, and a second dose 1 month after the first is often used for this. In practice, the management of pin-worm infection can be very difficult, with patients re-attending with re-infection on several occasions. Pharmacological treatment should be given only when it is associated with suitable advice on adequate hygiene and handwashing, ensuring that children and adults keep fingernails clipped short. It may be helpful to encourage children to wear gloves at night to assist in breaking the infection cycle.
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