Quetiapine Seroquel

1. Quetiapine is an atypical neuroleptic with a very low incidence of EPS.

2. Initial dose is 25 mg bid, which is titrated every 1 or 2 days to a total daily dose of 300-400 mg (given bid or tid).

3. Side effects include orthostatic hypotension, somnolence, and weight gain. Dyspepsia, abdominal pain, and dry mouth may also occur.

4. Initial and periodic eye exams (with slit lamp) are recommended because of the occurrence of cataracts in very high dose animal studies.

5. Dosage should be reduced in the elderly. Sustained prolactin elevation is not observed.

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Conquering Fear In The 21th Century

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