1. Meets basic diagnostic criteria for Dementia but also:
a. The deficits persists beyond the usual duration of substance intoxication or withdrawal.
b. There is evidence that the deficits are related to the persisting effects of substance use (specify which drug or medication).
2. When drugs of abuse are involved, most patients have, at some time in their lives, met criteria for substance dependence.
3. Clinical presentation is that of a typical dementia. Occasionally patients will improve mildly after the substance use has been discontinued, but most display a progressive downhill course.
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