Differential Diagnosis of Premenstrual Dysphoric Disorder

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A. Premenstrual Syndrome. Many females experience mild transient affective symptoms around the time of their period. PMDD is diagnosed only when symptoms lead to marked impairment in social and occupational functioning.

B. Premenstrual Exacerbation of a Current Mood or Anxiety Disorder. Females with disorders such as dysthymia or generalized anxiety disorder may experience a premenstrual exacerbation of their depressive or anxiety symptoms. These individuals will continue to meet criteria for a mood or anxiety disorder throughout the menstrual cycle whereas patients with PMDD have symptoms only prior to and during menses.

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