Monoamine Oxidase Inhibitors

a. Contraindications and dietary restriction discourage common use.

b. Side Effects. Orthostatic hypotension is common. A tyramine-free diet is required to prevent hypertensive crisis.

c. Drug Interactions. Coadministration of epinephrine, meperidine, and SSRIs can be life-threatening.

VII. Electroconvulsive Therapy for Depression (also see Electroconvulsive Therapy, page 121). ECT is a safe and effective treatment for depression, especially if there is a high risk for suicide or insufficient time for a trial of medication.

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