Negative symptoms

a. Poverty of speech (alogia) or poverty of thought content b. Anhedonia c. Flat affect d. Loss of motivation (avolition)

e. Attentional deficits f. Loss of social interest

3. Depression is common and often severe in schizophrenia and can compromise functional status and response to treatment. Atypical antipsychotics often improve depressive signs and symptoms, but antidepressants may be required.

4. Cognitive impairment. Cognitive dysfunction (including attention, executive function, and particular types of memory) contribute to disability and can be an obstacle in long-term treatment. There is evidence that the atypical antipsychotics improve cognitive impairment.

C. The presence of tactile, olfactory or gustatory hallucinations may indicate an organic etiology such as complex partial seizures.

D. Sensorium is intact.

E. Insight and judgment are frequently impaired.

F. No sign or symptom is pathognomonic of schizophrenia.

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