a. When the mood disorder is associated with recent or prolonged substance use or withdrawal from a substance and psychotic symptoms, a substance-induced mood should be diagnosed.
b. Blood or urine screens may be helpful in establishing this diagnosis.
c. Common substances that can cause depressive syndromes include antihypertensives, hormones (cortisone, estrogen, progesterone), antiparkinsonian drugs, benzodiazepines, alcohol, chronic use of sympathomimetics, and withdrawal from psychostimulants.
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