A. Hospitalization is usually not required unless suicidality is present.
B. Antidepressants. Many patients respond well to antidepressants. SSRIs are most often used. If these or other antidepressants such as venlafaxine, nefazodone or bupropion have failed, then a tricyclic antidepressant such as desipramine, 150 to 200 mg per day is often effective. (For a complete discussion of antidepressant therapy, page 109)
C. Psychotherapy: Cognitive psychotherapy may help patients deal with incorrect negative attitudes about themselves. Insight oriented psychotherapy may help patients resolve early childhood conflicts that have precipitated depressive symptoms. Combined psychotherapy and pharmacotherapy produces the best outcome.
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