Women attending antenatal clinics are a low-risk population for STI and the magnitude of changes in prevalence among 15-24-year-olds may thus be relatively small. Observed changes may not achieve statistical significance, even with a 3-5 year interval between surveys.

In some countries, or in certain areas within countries, a substantial number of women do not have antenatal care. Moreover, infertile and non-pregnant women are excluded when generating this indicator. Representativeness for the overall population and the proxy value for estimating STI prevalence are thus limited.

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