Introduction

DPI has been used to study a wide range of molecular systems. These range from studying the interfacial behaviour and orientation of pro-

4700 4800 ¿1900 5000 5100 5200 5300 5400 5500

Fig. 1. Dual polarisation interferometry (DPI) experiment showing the thickness (thin black line), density (thin grey line) and mass (thick black line) profiles for a layer constructed of 80 nm silica nanospheres

4700 4800 ¿1900 5000 5100 5200 5300 5400 5500

Fig. 1. Dual polarisation interferometry (DPI) experiment showing the thickness (thin black line), density (thin grey line) and mass (thick black line) profiles for a layer constructed of 80 nm silica nanospheres tein molecules and the solid-liquid interface to the molecular interactions of model systems such as biotin-streptavidin, and subsequent structural changes through to the structural changes invoked when certain proteins bind metal ions. A selection of applications has been chosen for discussion here that illustrate the wide range of orientation and interaction studies that can be undertaken using DPI.

Was this article helpful?

0 0

Post a comment