In general it is best from an analytical perspective to undertake as much of the experimental procedure as possible on the DPI instrument itself. Thus, all chemistries that can be carried out across a typical temperature range of 10-40 °C in the liquid phase can in principle be undertaken on the instrument. The advantage of running entire experiments "on-instrument" is simple: it enables a very clear analysis of how much of each material is deposited on the sensor surface at each stage of the experimental procedure and under what conditions. This enables the use of very valuable diagnostic information when analysing the experimental data, and enables stoichiometric analysis of the interactions investigated to be undertaken with ease.
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