Studies have supported that regular use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, Nuprin), naproxen sodium (Aleve), and indomethacin (Indocin) may reduce AD risk by 30 to 60 percent.
Researchers are also studying the antioxidant affects of vitamin E and selegiline hydrochloride in preventing brain damage caused by toxic free radicals to slow the rate of progression of AD. Studies of estrogen replacement therapy in menopausal women showed a reduced risk of developing AD by 30 to 40 percent. In 2002, a synthetic form of beta-amyloid protein (AN-1792) vaccine was being investigated in clinical trials.
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