Cardiac Output

There was no statistically significant difference among the three groups in changes from baseline to week 12 in cardiac output measured at trough levels (p=0.051), so no further statistical comparisons were carried out. The treatment effects at trough levels were -1.0 l/min (95% CI -2.1 to 0.1) and 0.5 l/min (95% CI -0.8 to 1.9) for the lower and higher doses of sildenafil compared with placebo. When patients receiving sildenafil were combined into a single treatment group, cardiac output at trough levels was reduced by was -0.4 l/min (95% CI -1.6 to 0.7) but was not significantly different from placebo. No statistically significant difference was observed among the three groups in changes from baseline to week 12 in cardiac output measured at 1 hour post-dose. The respective treatment effects for the lower and higher doses of sildenafil compared with placebo at 1 hour post-dose were -0.6

l/min (95% CI -1.8 to 0.6) and -0.2 l/min (95% CI -1.2 to 1.6). For the combined sildenafil treatments the effect size was -0.3 l/min (95% CI -1.4 to 0.8) for 1 hour post-dose.

Dealing With Erectile Dysfunction

Dealing With Erectile Dysfunction

Whether you call it erectile dysfunction, ED, impotence, or any number of slang terms, erection problems are something many men have to face during the course of their lifetimes.

Get My Free Ebook


Post a comment