Diagnosis

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Typical PHAHD is not difficult to diagnose. The infant presents a history of born or brought up to high altitude, the findings of a severe pulmonary hypertension (MPAP > 4 kPa or 30 mmHg, via noninvasive echo-Doppler, or catheterization ), right ventricular hypertrophy and congestive heart failure support the diagnosis of PHAHD. However, PHAHD may be most readily confused with primary pulmonary hypertension (PPH) and congenital heart disease at high altitude.

TABLE 2. Cardiac catheterization data in infants or children with severe pulmonary hypertension in mountainous areas of the world

Pulmonary artery pressure (mmHg)

TABLE 2. Cardiac catheterization data in infants or children with severe pulmonary hypertension in mountainous areas of the world

Pulmonary artery pressure (mmHg)

Altitude

Subject

Systolic

Diastolic

Mean

Reference

Leadville-Climax

Six white infants and

70.8 ± 27

30 ± 26

47 ± 24

(16)

CO, 3360-3890m

Children, 6-17 months

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Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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