Hemodynamics And Pathology

In 1963, with the name of "primary pulmonary hypertension in children living at high altitude", Khoury and Hawes reported their findings in 11 infants from 6 to 23 months living in Leaville, Colorado (3,100 m). Five of them were moved to Denver, Colorado (1500 m) and had cardiac catheterization with an average mPAP of 44 mm Hg and a range of 28-72 mm Hg. Post-mortem studies in two patients showed severe RVH and marked hypertrophy of the medial muscular coat and intimal proliferation, but not occlusive lesions [25]. In the following years Tibetan investigators described similar pathological findings in 57 infants who died with the diagnosis of pediatric HAHD [28] and several years later, the same authors extended their investigations to 100 infants with HAHD [27]. Lin and Wu published their clinical observations in 286 cases of pediatric HAHD [30].

TABLE 8. Pulmonary arterial pressure in infants with subacute mountain sickness while

recovering at lower altitudes

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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