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Values for mPAP are mean or mean ± SD. tDoppler echocardiography in Xining, 2260 m. ^Cardiac catheterization in Denver, 1500 m.

Values for mPAP are mean or mean ± SD. tDoppler echocardiography in Xining, 2260 m. ^Cardiac catheterization in Denver, 1500 m.

The first report in English with the name of Subacute Mountain Sickness (SMS) was published in 1988 by Asian and British investigators who placed emphasis on the subacute evolution of this disease and reported the postmortem findings in 15 infants. Extreme medial hypertrophy of the small pulmonary arteries and massive hypertrophy and dilatation of the right ventricle were the main factors [70]. Some hemodynamic studies have been undertaken in SMS.

Wu and Miao reported an average mPAP of 33 mm Hg in 8 infants living at 3000-4000 m and recovering from SMS in Xining (2261 m) [76]. Recently, a moderate to severe PH with a mPAP of 72 mmHg was assessed by Doppler-echocardiography in 55 infants coming from high altitudes and recovering from SMS in Xining [66] (Table 8). SMS in adults has also been described in soldiers patrolling at very high altitudes of the Himalayan mountains, with prompt recovery after moving down to lower levels [2]. A comprehensive review of SMS has recently been published [3]. SMS is not frequent in the Andes but some observational cases have been described in Peru and Bolivia [24,44,56].

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Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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