Surgical resection remains the most effective therapy for colorectal carcinoma, and the best estimation of prognosis is related to the pathologic findings on the resected specimen . These parameters are best evaluated by a standardised sampling and by a standard pathology report or checklist [21-23] (Table 1). The pathologic report should provide all the relevant information needed to assess the stage of disease including grade, extent of invasion, presence of extramural vascular invasion, configuration of tumour borders and the presence of a peritumoral lymphocytic response (Table 2). Microscopic assess ment of margins and lymph nodes must also be included [3, 22].
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