Unfavourable Histology

The presence of budding (islets of focal dedifferenti-ated cancer) at the invasive front or signs of signet-ring-cell adenocarcinoma, or both elements, are histopathologic findings referred to as unfavourable histology, bearing a higher risk of nodal involvement and ultimately of adverse outcome, as evidenced in some recent Japanese works [11-13]. Masaki et al. reported unfavourable histology to be the only prognostic factor significantly related to lymph node metastasis in T1 and T2 rectal carcinoma undergoing LE or radical surgery [13].

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Dealing With Erectile Dysfunction

Dealing With Erectile Dysfunction

Whether you call it erectile dysfunction, ED, impotence, or any number of slang terms, erection problems are something many men have to face during the course of their lifetimes.

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