Problems associated with ocular gene expression

Analysis of gene expression in ocular tissues has highlighted a number of potential problems, some of which are specific to the eye, and others that are not unique to this tissue. These may be broadly summarized as:

a) light sensitivity b) RNA quantity c) RNA quality d) cellular heterogeneity e) multiple target genes f) biological variance

These problems are expanded upon below, and possible resolutions are discussed in the following sections.

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