(1) Increases in blood volume or decreases in venous compliance increase mean systemic pressure, shifting the venous return curve to the right in a parallel fashion (Figure 3-13). A new equilibrium, or intersection, point is established at which both cardiac output and right atrial pressure are increased.
(2) Decreases in blood volume (e.g., hemorrhage; not illustrated) or increases in venous compliance have the opposite effect— decreased mean systemic pressure and a shift of the venous return curve to the left in a parallel fashion. A new equilibrium point is established at which both cardiac output and right atrial pressure are decreased.
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