BNorepinephrine epinephrine and dopamine Figure 17 1 Norepinephrine

- is the primary transmitter released from postganglionic sympathetic neurons.

- is synthesized in the nerve terminal and released into the synapse to bind with a or p receptors on the postsynaptic membrane.

-is removed from the synapse by reuptake or is metabolized in the presynaptic terminal by monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT). The metabolites are:

(a) 3,4-Dihydroxymandelic acid (DOMA)

(b) Normetanephrine (NMN)

(c) 3-Methoxy-4-hydroxyphenylglycol (MOPEG)

Tyrosine | tyrosine hydroxylase

L-dopa I dopa decarboxylase

Dopamine | dopamine ß-hydroxylase

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Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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