CChanges in TPR change both the cardiac output and the venous return curves

Positive inotropic effect

Positive inotropic effect

Cardiac output

Cardiac output

Mean systemic pressure

Right atrial pressure (mm Hg) or end-diastolic volume (L)

Figure 3-12. Effect of a positive inotropic agent on the cardiac function curve, cardiac output, and right atrial pressure.

Mean systemic pressure

Right atrial pressure (mm Hg) or end-diastolic volume (L)

Figure 3-12. Effect of a positive inotropic agent on the cardiac function curve, cardiac output, and right atrial pressure.

Right atrial pressure (mm Hg) or end-diastolic volume (L)

Figure 3-13. Effect of increased blood volume on the mean systemic pressure, vascular function curve, cardiac output, and right atrial pressure.

- Changes in TPR alter both curves simultaneously; therefore, the responses are more complicated than those noted in the previous examples.

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