- stimulate the carotid body peripheral chemoreceptors directly, independent of changes in Pco2.
- In metabolic acidosis, breathing rate is increased (hyperventilation) because arterial [H+] is increased and pH is decreased.
Table 4-6. Comparison of Central and Peripheral Chemoreceptors
Stimuli that Increase Breathing Rate
Central chemoreceptors l pH
Carotid and aortic bodies
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