D Effects of ECF volume on proximal tubular reabsorption

(1) ECF volume contraction increases reabsorption. Volume contraction increases peritubular capillary protein concentration and ttc, and decreases peritubular capillary Pc. Together, these changes in Starling forces in peritubular capillary blood cause an increase in proximal tubular reabsorption.

(2) ECF volume expansion decreases reabsorption. Volume expansion decreases peritubular capillary protein concentration and ttc, and increases Pc. Together, these changes in Starling forces in peritubular capillary blood cause a decrease in proximal tubular reabsorption.

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