- is prominent in midbrain neurons.
- is released from the hypothalamus and inhibits prolactin secretion.
-is metabolized by MAO and COMT.
- Dj receptors activate adenylate cyclase via a Gs protein.
- D2 receptors inhibit adenylate cyclase via a G, protein. -Parkinson's disease involves degeneration of dopaminergic neurons, which use the D2 receptors.
- Schizophrenia involves increased levels of D2 receptors.
Was this article helpful?