- Blood flow in skeletal muscle exhibits autoregulation and active and reactive hyperemia.
- Demand for 02 in skeletal muscle varies with metabolic activity level, and blood flow is regulated to meet demand.
- During exercise, when demand is high, these local metabolic mechanisms are dominant.
- The local vasodilator substances are lactate, adenosine, and K+.
- Mechanical effects during exercise temporarily compress the arteries and decrease blood flow. During the postocclusion period, reactive hyperemia increases blood flow to repay the 02 debt.
- has extensive sympathetic innervation. Cutaneous blood flow is under extrinsic control.
- Temperature regulation is the principal function of the cutaneous sympathetic nerves. Increased ambient temperature leads to cutaneous vasodilation, allowing dissipation of excess body heat.
- Trauma produces the "triple response" in skin—a red line, a red flare, and a wheal. A wheal is local edema that results from the local release of histamine, which increases capillary filtration.
Was this article helpful?