Steps in transduction in the olfactory receptor neurons

a. Odorant molecules bind to receptors located on cilia of the olfactory-receptor neurons.

b. When the receptors are activated, they activate G proteins, which in turn activate adenylate cyclase.

c. There is an increase in intracellular [cAMP] that opens Na+ channels in the olfactory receptor membrane and produces a depolarizing receptor potential.

d. The receptor potential depolarizes the initial segment of the axon to threshold, and action potentials are generated and propagated.

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