Total body water

Intracellular

Extracellular

Extracellular

Figure 5-1. Body fluid compartments.

Plasma

Interstitial

Table 5-1. Body Water and Body Fluid Compartments

Body Fluid Compartment

Fraction of TBW*

Markers Used to Measure Volume

Major Cations

Major Anions

TBW

d2o

Inulin

Mannitol

hco3-

Plasma

1/12 (1/4 of ECF)

RISA Evans blue

Plasma protein

Interstitial

1/4 (3/4 of ECF)

ECF - plasma volume (indirect)

Na+

hco3-

ICF

2/3

TBW - ECF (indirect)

K+

Organic phosphates Protein

"Total body water (TBW) is approximately 60% of total body weight or 42 L in a 70-kg man. ECF = extracellular fluid; ICF = intracellular fluid; RISA = radioiodinated serum albumin.

"Total body water (TBW) is approximately 60% of total body weight or 42 L in a 70-kg man. ECF = extracellular fluid; ICF = intracellular fluid; RISA = radioiodinated serum albumin.

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