Nuclear medicine imaging continues to have an established role in the management of patients with papillary and follicular thyroid cancers, with 131I scanning remaining the routine imaging technique for localizing remnant and recurrent disease. The development of recombinant human TSH offers increased flexibility for imaging and treatment, whilst reducing the side effects of thyroxine withdrawal. The newer radionuclide imaging techniques remain underutilized, despite good evidence for their sensitivity in detecting tumor recurrence. The development of new agents continues with the potential for new therapeutic agents. The importance of the development of evidence-based strategies for the optimal integration of radionuclide imaging in the diagnosis and follow-up of patients with thyroid cancers needs to be recognized.
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