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Thyroid Factor

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The majority of patients with a tumor size of more than 1cm diameter should have 131I ablation therapy. Pregnancy or breast-feeding must be excluded before radioactive iodine is administered.

Reassessment with a whole-body radioiodine scan (after stopping T4 for 4 weeks) is indicated 4-6 months after 131I ablation, although in low risk patients measurement of Tg alone may be adequate. If significant uptake of the tracer is detectable, a further 131I therapy dose should be given and a posttreatment scan obtained. Following this the patient should restart T4. If there is suspicion of residual disease, further scans should be carried out.

Radioiodine therapy should only be carried out in centers with appropriate facilities and will be administered by an oncologist (or nuclear medicine physician) who is a member of the MDT and holds an appropriate ARSAC (Administration of Radioactive Substances Advisory Committee) certificate.

Mortality from PTC Recurrence, Any Site

Mortality from PTC Recurrence, Any Site

Figure 2.2 Comparison of cumulative disease-specific mortality (left-hand panel) and recurrence (right-hand panel) between patients treated for papillary thyroid cancer by either unilateral lobectomy or bilobar resection. (From Hay ID, McConahey WM, Goell-ner JR Managing patients with papillary thyroid carcinoma: insights gained from the Mayo Clinic's experience of treating 2512 consecutive patients during 1940 through 2000. Transactions of the American Clinical and Climatological Association 2002;113:241-260.)

Figure 2.2 Comparison of cumulative disease-specific mortality (left-hand panel) and recurrence (right-hand panel) between patients treated for papillary thyroid cancer by either unilateral lobectomy or bilobar resection. (From Hay ID, McConahey WM, Goell-ner JR Managing patients with papillary thyroid carcinoma: insights gained from the Mayo Clinic's experience of treating 2512 consecutive patients during 1940 through 2000. Transactions of the American Clinical and Climatological Association 2002;113:241-260.)

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