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Ultrasound can also be used in the detection of recurrent thyroid malignancy (Figure 26.8). Local recurrence appears as a hypoechoic mass within the neck. It is usually ill defined. US-guided biopsy is usually possible and accurate [35].

Studies have also shown in the follow-up of differentiated thyroid carcinoma with serum thyroglobulin measurement that ultrasound

Figure 26.8 Needle biopsy of recurrent thyroid cancer.

significantly increases the sensitivity of tumor detection and may show lymph node metastases despite low thyroglobulin levels [36,37].

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