Ultrasound can also be used in the detection of recurrent thyroid malignancy (Figure 26.8). Local recurrence appears as a hypoechoic mass within the neck. It is usually ill defined. US-guided biopsy is usually possible and accurate .
Studies have also shown in the follow-up of differentiated thyroid carcinoma with serum thyroglobulin measurement that ultrasound
significantly increases the sensitivity of tumor detection and may show lymph node metastases despite low thyroglobulin levels [36,37].
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