With the exception of doxycycline, antimalarials, includ ing primaquine, are safe for children when administered at the prescribed dose. Children and adolescents are at special risk of malaria, perhaps because of poor compliance or inaccurate calculation of the dose (Adera et al., 1995), and they may rapidly become seriously ill. Babies, including breast-fed infants, and children should be well protected against mosquito bites and receive malaria chemoprophylaxis. Children are at greater risk than adults for N,N-diethyl-rn-toluamide (DEET) toxicity, which includes seizures among other central nervous system abnormalities.
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