Glass Transitions In Proteins

Expansivity Glass

The idea that water acts as a plasticizer of the protein conformation is not new it was suggested many years ago by Bone and Pethig 102 on the basis of dielectric relaxation studies (see Chapter 4). In recent years, several studies of fully hydrated proteins and protein crystals also have indicated the existence of a glasslike dynamical transition at about 200 K in proteins. It is well known that glass transition temperatures for synthetic polymers decrease with increases in plasticizer...